
产品货号:
Z10550
中文名称:
AHNAK抗体
英文名称:
Anti-AHNAK Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AHNAK Antibody |
指标别名 | AHNAK;AHNAK nucleoprotein;AHNAKRS;Desmoyokin;PM227 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | IHC |
基因名称 | AHNAK |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human AHNK protein. |
计算分子量 | 629KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | AHNK antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | AHNAK1 (Desmoyokin) is a large (700kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels.AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation.In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane,connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture.In epithelial cells,AHNAK1 is localized in cytoplasm or is membrane-associated,but in cells of nonepithelial origin AHNAK1 is predominantly nuclear;it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex. |
Uniprot ID | Q09666 |
基因名全称 | Neuroblast differentiation-associated protein AHNAK |
蛋白名全称 | Neuroblast differentiation-associated protein AHNAK |
推荐稀释比 | IHC-p 1:50~300 |
相关搜索:AHNAK抗体,AHNAK多抗,Anti-AHNAK Antibody